Publications

Badi I, Antoniades C. Brown Adipose Tissue and the Take (12,13-di)HOME Message to the Heart. Circulation. 2021 Jan 12;143(2):160-162.


Antoniades C, Asselbergs FW, Vardas P. The year in cardiovascular medicine 2020: digital health and innovation. Eur Heart J. 2021 Feb 14;42(7):732-739.


Kotanidis CP, Antoniades C. Selfies in cardiovascular medicine: welcome to a new era of medical diagnostics. Eur Heart J. 2020 Dec 7;41(46):4412-4414.


Oikonomou EK, Desai MY, Marwan M, Kotanidis CP, Antonopoulos AS, Schottlander D, Channon KM, Neubauer S, Achenbach S, Antoniades C. Perivascular Fat Attenuation Index Stratifies Cardiac Risk Associated With High-Risk Plaques in the CRISP-CT Study. J Am Coll Cardiol. 2020 Aug 11;76(6):755-757.


West HW, Antoniades C. Imaging and Targeting Coronary Artery Inflammation. Antioxid Redox Signal. 2021 May 20;34(15):1217-1243. doi: 10.1089/ars.2020.8128. Epub 2020 Jun 18.


Akoumianakis I, Badi I, Douglas G, Chuaiphichai S, Herdman L, Akawi N, Margaritis M, Antonopoulos AS, Oikonomou EK, Psarros C, Galiatsatos N, Tousoulis D, Kardos A, Sayeed R, Krasopoulos G, Petrou M, Schwahn U, Wohlfart P, Tennagels N, Channon KM, Antoniades C. Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition. Sci Transl Med. 2020 Apr 29;12(541).

Abstract: http://stm.sciencemag.org/cgi/content/abstract/12/541/eaav8824?ijkey=p1DZG1wuYRP2Y&keytype=ref&siteid=scitransmed

Reprint: http://stm.sciencemag.org/cgi/rapidpdf/12/541/eaav8824?ijkey=dphuJ5mmKQqU2&keytype=ref&siteid=scitransmed

Full text: http://stm.sciencemag.org/cgi/content/full/12/541/eaav8824?ijkey=dphuJ5mmKQqU2&keytype=ref&siteid=scitransmed


Akoumianakis I, Sanna F, Margaritis M, Badi I, Akawi N, Herdman L, Coutinho P, Fagan H, Antonopoulos AS, Oikonomou EK, Thomas S, Chiu AP, Chuaiphichai S, Kotanidis CP, Christodoulides C, Petrou M, Krasopoulos G, Sayeed R, Lv L, Hale A, Naeimi Kararoudi M, McNeill E, Douglas G, George S, Tousoulis D, Channon KM, Antoniades C. Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases. Sci Transl Med. 2019;11(510).


Oikonomou EK, Williams MC, Kotanidis CP, Desai MY, Marwan M, Antonopoulos AS, Thomas KE, Thomas S, Akoumianakis I, Fan LM, Kesavan S, Herdman L, Alashi A, Centeno EH, Lyasheva M, Griffin BP, Flamm SD, Shirodaria C, Sabharwal N, Kelion A, Dweck MR, Van Beek EJR, Deanfield J, Hopewell JC, Neubauer S, Channon KM, Achenbach S, Newby DE, Antoniades C. A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography. Eur Heart J. 2019. Sep 3. pii: ehz592. 


Oikonomou EK., Marwan M., Desai MY., Mancio J., Alashi A., Hutt Centeno E., Thomas S., Herdman L., Kotanidis CP., Thomas KE., Griffin BP., Flamm SD., Antonopoulos AS., Shirodaria C., Sabharwal N., Deanfield J., Neubauer S., Hopewell JC., Channon KM., Achenbach S., Antoniades C. Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data. Lancet. 2018 Sep 15;392(10151):929-939. 


Antonopoulos AS., Sanna F., Sabharwal N., Thomas S., Oikonomou EK., Herdman L., Margaritis M., Shirodaria C., Kampoli A-M., Akoumianakis I., Petrou M., Sayeed R., Krasopoulos G., Psarros C., Ciccone P., Brophy CM., Digby J., Kelion A., Uberoi R., Anthony S., Alexopoulos N., Tousoulis D., Achenbach S., Neubauer S., Channon KM., Antoniades C. Detecting human coronary inflammation by imaging perivascular fat. Sci Transl Med. 2017 Jul 12;9(398). 


Margaritis M., Sanna F., Lazaros G., Akoumianakis I., Patel S., Antonopoulos AS., Duke C., Herdman L., Psarros C., Oikonomou EK., Shirodaria C., Petrou M., Sayeed R., Krasopoulos G., Lee R., Tousoulis D., Channon KM., Antoniades C. Predictive value of telomere length on outcome following acute myocardial infarction: evidence for contrasting effects of vascular vs. blood oxidative stress. Eur Heart J. 2017;38(41):3094-3104.


Antonopoulos AS, Margaritis M, Verheule S, Recalde A, Sanna F, Herdman L, Psarros C, Nasrallah H, Coutinho P, Akoumianakis I, Brewer AC, Sayeed R, Krasopoulos G, Petrou M, Tarun A, Tousoulis D, Shah AM, Casadei B, Channon KM and Antoniades C. Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-gamma/Adiponectin Signalling. Circ Res. 2016;118:842-55.


Karimi Galougahi K, Antoniades C, Nicholls SJ, Channon KM and Figtree GA. Redox biomarkers in cardiovascular medicine. Eur Heart J. 2015;36:1576-82, 1582a-b.


Antonopoulos AS, Margaritis M, Coutinho P, Shirodaria C, Psarros C, Herdman L, Sanna F, De Silva R, Petrou M, Sayeed R, Krasopoulos G, Lee R, Digby J, Reilly S, Bakogiannis C, Tousoulis D, Kessler B, Casadei B, Channon KM and Antoniades C. Adiponectin as a link between type 2 diabetes and vascular NADPH oxidase activity in the human arterial wall: the regulatory role of perivascular adipose tissue. Diabetes. 2015;64:2207-19.


Antonopoulos AS, Margaritis M, Coutinho P, Digby J, Patel R, Psarros C, Ntusi N, Karamitsos TD, Lee R, De Silva R, Petrou M, Sayeed R, Demosthenous M, Bakogiannis C, Wordsworth PB, Tousoulis D, Neubauer S, Channon KM and Antoniades C. Reciprocal effects of systemic inflammation and brain natriuretic peptide on adiponectin biosynthesis in adipose tissue of patients with ischemic heart disease. Arterioscler Thromb Vasc Biol. 2014;34:2151-9.


Antoniades C and Channon KM. Statins: pleiotropic regulators of cardiovascular redox state. Antioxid Redox Signal. 2014;20:1195-7.


Margaritis M, Channon KM and Antoniades C. Statins as regulators of redox state in the vascular endothelium: beyond lipid lowering. Antioxid Redox Signal. 2014;20:1198-215.


Margaritis M, Antonopoulos AS, Digby J, Lee R, Reilly S, Coutinho P, Shirodaria C, Sayeed R, Petrou M, De Silva R, Jalilzadeh S, Demosthenous M, Bakogiannis C, Tousoulis D, Stefanadis C, Choudhury RP, Casadei B, Channon KM and Antoniades C. Interactions between vascular wall and perivascular adipose tissue reveal novel roles for adiponectin in the regulation of endothelial nitric oxide synthase function in human vessels. Circulation. 2013;127:2209-21.

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